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Home NEWS The researchers hope that it can help in the diagnosis and prognosis of pleural mesothelioma.

The researchers hope that it can help in the diagnosis and prognosis of pleural mesothelioma.

10 October 2012 - In a pioneering study, published in the New England Journal of Medicine today, dear mesothelioma researchers led by Harvey I. Pass, MD, of the Medical Center of New York University, said that they have identified biomarkers in blood and effusion (effusion refers to the exit of fluid from the blood vessels or the lymphatic system and its collection in the body cavity), which can distinguish between the impact of a healthy person Asbestos mesothelioma patients and distinguish effusions caused by mesothelioma from other malignant and benign effusions.

Blood and effusion fluids were collected doctors in Detroit and New York, in patients with pleural mesothelioma, in patients with a pleural effusion is not due to mesothelioma and cancer-free individuals with a history of asbestos exposure (including foundry, mechanics, plumbers, ship builders, machinists , tool and die workers, fitters, masons, electricians, those in the building trades, those involved in the assembly or repair, those with exposure to vermiculite insulation, and those with exposure from contact with family members who have worked with asbestos) . The study compared the levels of biomarkers called fibulin-3 in the blood, and the outpouring of the different groups of patients. They found that fibulin-3 in the blood does not vary according to age, sex or duration of exposure to asbestos. Fibulin-3 in the blood was significantly higher, however, in patients with pleural mesothelioma than in asbestos-exposed individuals without mesothelioma. In addition, fibulin-3 levels in the effusion fluid were significantly higher in patients with pleural mesothelioma than in patients with effusion caused by something else.

These results show that the levels of fibulin-3 in the blood plasma and effusion may help in the diagnosis and prognosis of pleural mesothelioma. The authors noted that further research on fibulin-3 are necessary before it can be used to diagnose patients in a clinical setting. They also called for further study of how fibulin-3 can be used to predict the prognosis of patients.

The authors called for further study of this important biomarker in order to clarify the role of fibulin-3 in the growth of mesothelioma, invasion and metastasis formation and to determine whether a molecule can be designed for a specific therapy. This study is an exciting promise of potentially improving the effectiveness of treatment, doctors can offer patients with mesothelioma.

This study is the result of collaboration of physicians from the New York University Langone Medical Center, Mount Sinai School of Medicine, Karmanos Cancer


Institute, University of Hawaii Cancer Center, University of California, Los Angeles, Swedish Cancer Institute, Fred Hutchinson Cancer Research Center, Princess Margaret Hospital, University Health Network and University of Toronto.
Levy Phillips & Konigsberg LLP are proud to have contributed to the support of this research through our donations.


WARNING: Mesothelioma has no known cure and often causes severe pain, suffering, and other damages, such as loss of consortium and loss of income. In addition, due to the extremely high cost of treatment of mesothelioma, many families exhaust savings and accumulation of financial debt to pay for the medical expenses of their family members.
In accordance with the law of most states, the pain and suffering from mesothelioma can be compensated by an award of monetary damages are usually obtained with the help of experienced lawyers mesothelioma. In some states, other types of damage can be repaired.
Asbestos Mesothelioma court allows victims to obtain financial compensation and to prosecute companies that caused their asbestos exposure.


IMPORTANT: If you or a family member has been diagnosed with mesothelioma, you should get in touch with a mesothelioma lawyer as soon as possible to determine if you have a mesothelioma case, as well as:
Save your right to bring a lawsuit against the responsible parties in the limited time allowed by law, known as the statute of limitations;Get maximum compensation in your case, being able to:Preserve evidence and establish the facts of asbestos exposure while the claimant is still alive and able to provide information;File and resolve a lawsuit against the responsible parties before they file for bankruptcy or if they already have to be compensated up to their bankruptcy trust funds run out of money;Speed ​​up your case, the courts tend to give a higher priority to mesothelioma claims, the applicant is still alive.Find out if you have a case, speak to one of our experienced mesothelioma lawyers through our 24/7 toll free hotline 1-800-MESO-LAW (1-800-637-6529) or by submitting an e-mail request (see education is higher). Our attorneys will quickly respond to you and happy to answer all your questions.
NOTE: While our offices are located in the states of New York, New Jersey, Georgia and California, many of our mesothelioma lawyers licensed to practice law in a number of U.S. states and have the ability and extensive experience representing clients throughout the United States mesothelioma.

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