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Mesothelioma asbestos Cancer - a tumor that develops from cells of the mesothelium. This epithelial tissue, which is located above the connective tissue covering or lining the body cavities: the pleura, the pericardium (heart cavity), the peritoneum.

At first glance, it seems that mesothelioma asbestos Cancer is not anything scary - it's pretty dense tissue, the cells of which are very close contact with each other. In fact, the mesothelial cells are very sensitive and prone to failure, replacement of other cell types.

Mesothelioma asbestos Cancer - The tumor is usually malignant, early metastasis, commonly invades adjacent structures.

Causes

Malignant mesothelioma asbestos Cancer (also called carcinosarcoma, endotelioma) often develops in the pleura, less frequently in the endothelium of the peritoneum and casuistically - the pericardium. Cause of malignant transformation of epithelial tissue - contact with asbestos dust and smoking (carcinosarcoma pleura), the same reasons, plus injuries of the abdomen and lead to disembriogenez sarcoma mesothelium of the peritoneum and pericardium.

In the development of this cancer pathology report great role of ionizing radiation, and silicates, wax, do not exclude the viral nature of the disease.

Symptoms

Tumor, localized in the pleura, gives symptoms almost from the first stage: cough, chest pain, pleurisy. But as a rule, the symptoms are for "cold", treated as "normal" cough, blamed the symptoms of chronic bronchitis or smoker's cough.

At this time, the cancer cells metastasize quickly, and the tumor increases in size, light squeezes, impairs blood circulation, which leads to the progression of pleurisy, the appearance of dyspnea.

Picture of the tumor of the peritoneum is not distinct, erased. A feeling of heaviness in the abdomen obscure location, periodic instability stool, sensation of a lump in the supine position. Then, with the progression of the process, pain, nausea, stool disorders are permanent, develop ascites.

For this disease at any site is typical fever, a slight increase in temperature (not above subfebrile), but permanent. About half the patients complain of pain in the small joints, describing them as volatile and more disturbing in the morning.

Diagnosis and Treatment

Mesothelioma asbestos Cancer diagnosis is complex, and, given the rapid growth of the tumor and its aggressiveness, accurate diagnosis is often placed only on the results of the autopsy. Life history, including indication that we had in the past exposure to asbestos or the manufacture (the presence of asbestos cement materials in the house, living near the active site of the plants or quarries, etc.) should always be cautious.

For diagnosis requires a combination of diagnostic tests: x-ray of the pleura or peritoneum, a computer, or magnetic resonance imaging, laparoscopic examination (thoracoscopy, paracentesis). For invasive diagnostic procedures required in order to remove tissue of cytological and histological examination.

Treatment of mesothelioma asbestos Cancer difficult, as a rule, multi-port, combined, include chemotherapy, surgical removal of part of the body, radiation, biotherapy. The tactics chosen physician based on a variety of factors, including the patient's general condition, the stage of the tumor.

Forecast

The prognosis is poor. Mesothelioma asbestos Cancer is growing very rapidly, hematogenous and lymphatic metastasis by an average survival rate of less than 1 year after the beginning of the process.

Mesothelioma asbestos Cancer - a malignant (more) tumor that grows from the mesothelial tissue with areas of sarcomatoid spindle-shaped cells and adenomatous tissue. Typically, the tumor is found in the pleura and peritoneum, at least - in the testis and joints. It grows as a thick layer covering the internal organs, and is composed of spindle-shaped cells and fibrous tissue.

Risk factors: prolonged exposure to asbestos, smoking.

Classification

  • · Benign Mesothelioma asbestos Cancer - Mesothelioma nonmetastasizing as a node on a stem or a broad base
  • ·
  • ·

• Clinical features: dyspnea (associated with exudative pleurisy), chest pain (due to tumor invasion into intercostal space), cough and hemoptysis, weight loss. Diagnosis: radiography of the chest, pleural puncture, evacuation and effusion cytology, biopsy and thoracoscopy.

• TNM-classification (applies only to tumors of the pleural cavity, see also tumor stage)

• • Tx - insufficient data to assess the primary tumor

• • T0 - the primary tumor is not determined

• • T1 - Tumor limited to the parietal and / or visceral pleura one side

• • T2 - the tumor grows on the affected side: lung, hilar fascia, diaphragm, pericardium

• • T3 - tumor grows on the side of destruction: the muscles of the chest wall, ribs, mediastinum

• • T4 - Tumor directly invades any of the following structures: reverse lung, pleura on the opposite side, the peritoneum, the abdominal organs, tissues of the neck

• • N0 - no metastases in regional lymph nodes

• • N1 - Metastasis in peribronchial and / or hilar lymph nodes on the affected side, including direct germination

• • N2 - metastases to mediastinal lymph nodes on the affected side and / or bifurcation (subkarinalnye)

• • N3 - metastasis to lymph nodes or mediastinal root of the lung on the opposite side; preskalennye or supraclavicular (either side).

• Grouping by stage

• Stage I: T1-2N0M0

• Stage II: T1-2N1M0

• Phase III

• • T1-3N2M0

• • T3N0-2M0

• Phase IV

• • T1-3N3M0

• • T4N0-3M0

• • T1-4N0- 3M1.

• Treatment

• Radical treatment is possible only with the surgical removal of limited forms of mesothelioma, which is rarely possible to perform operations

• The volume can range from excision of the tumor of the pleura with the underlying tissues to plevropulmonektomii, which, however, does not improve long-term outcomes

• The primary treatment for most patients - chemotherapy different combinations of drugs with the use of platinum (not developed standard procedures), including intrapleural administration. Pleural puncture or installation mikrodrenazha

• thiotepa 20 mg in 6.8 mL of 0.9% sodium chloride intraplevralno 01.02 p / week

• • pleurodesis: thoracoscopy with talcum powder or spray treatment with tetracycline in order to obliterate the pleural cavity

• Radiotherapy characterized by low efficiency.

• The prognosis is poor, the tumor is growing quickly, early spread to mediastinal lymph nodes.

Localized fibrous mesothelioma (solitary fibrous tumor) is formed mainly from the visceral pleura. Most of these tumors are benign, that defines a completely favorable prognosis • Clinical features: chest discomfort, dyspnea, pulmonary hypertrophic osteoarthropathy syndrome with arthralgia of the hands, elbows and knees, "drumsticks" (developed later) • Treatment: resection of the tumor, symptomatic treatment of hypertrophic pulmonary arthropathy.

Peritoneal mesothelioma asbestos Cancer occurs most often in men over 50 years old and is usually associated with asbestos exposure and appears enlarged abdomen, abdominal pain, nausea, vomiting and weight loss

• Diagnosis is established the detection of malignant cells in the exudate and biopsy specimens obtained during paracentesis, biopsies or laparotomy

• Treatment of localized forms of mesothelioma is that it is a radical surgical removal, in diffuse forms of surgical treatment is not indicated, use radiation or chemotherapy, or a combination, therapy is seldom effective.

Testicular mesothelioma asbestos Cancer (adenoma testicular adenofibroma testicle, testicular tumor adenomatous) - mesothelioma originating from the serous membrane of the testis, epididymis and its spermatic cord, characterized by a benign growth with the emergence ferum cavities.

Mesothelioma asbestos Cancer joint (Sinovioma, endotelioma synovial) - a tumor originating from the cells of the synovial tendon sheaths or mucous bags

• Sinovioma benign (giant tumor of tendon sheath, gigantoma tendon Sinovioma giant, Sinovioma ksantomatoznaya, sinovioendotelioma, tenosynovitis nodose) - a benign tumor of the tendon sheath (usually thumb), consisting of fibroblasts and giant cells

•Sinovioma malignant (synovial sarcoma, synovial sarkoendotelioma, sinovialoma malignant) based on the elements of the tendon sheaths, joints and mucous bags.

Friday, 12 October 2012 20:38

Mesothelioma - Cancer caused by asbestos.

Historically, there were many arguments about whether man made objects to cause health problems. By now, most of us would agree that it is very case. The relationship between  mesothelioma asbestos cancer, of course, was one of the relationships that have convinced people who had been in doubt.

Exactly where we begin by looking at the cancer mesothelioma? The first thing to grasp is - extremely terrifying kind of disease. This is sometimes referred to as really aggressive and rapid disease development, yet it can be completely wrong. It is - in fact quite slow growth, yet is about the most dangerous. As these statements may always be right? It comes down to the diagnosis. Cancer is incredibly difficult to diagnosis and can even develop for 45 years or maybe more, without being detected. When it is eventually identified, mesothelioma cancer is often still comes, there is nothing that can be done to save the patient.


Okay, so, what are the details of lousiness sand? Mesothelium - liner found in the trunk of the body. This liner acts as a protective shield for the internal organs in the body. It is made of several cell layers, which includes the form of motor oil in between them. This allows the physical security organs to move without being degraded, to wit, the abdomen to expand, the lungs to breathe, and the heart to beat and so on. As the term would suggest Mesothelioma - actually a tumor in this ship. Starting with liner runs throughout the middle and upper parts of the body the cancer can spread fairly easily.


The term Mesothelioma asbestos cancer is a kind of a misnomer. No single type of cancer. Instead, it is - the term used to touch subpopulation malignancies, which can be determined by wherever they strike the body. Pericardial Mesothelioma is known as a malignant growth involving mesotelium around the heart. Peritoneal Mesothelioma - Mesothelioma asbestos cancer is a malignant growth in the stomach. Pleural Mesothelioma - a malignant growth of cover higher waist, the surrounding area of ​​the lung, and are among the most frequent type of malignancy in this particular cancer. Additionally, there are some other rare cancer that can attack the city, such as the groin. They are so unusual, however, that we will not talk about them in this article.


Asbestos was once considered a miracle material for its heat-resistant properties and fired. Unfortunately, a review of the long term has shown that he has such properties, but they come at a crazy price. The price? Death for many of those who are working around the material in the form of Mesothelioma asbestos cancer. This - the price that no one should have to pay.

10 October 2012 - In a pioneering study, published in the New England Journal of Medicine today, dear mesothelioma researchers led by Harvey I. Pass, MD, of the Medical Center of New York University, said that they have identified biomarkers in blood and effusion (effusion refers to the exit of fluid from the blood vessels or the lymphatic system and its collection in the body cavity), which can distinguish between the impact of a healthy person Asbestos mesothelioma patients and distinguish effusions caused by mesothelioma from other malignant and benign effusions.
 

Blood and effusion fluids were collected doctors in Detroit and New York, in patients with pleural mesothelioma, in patients with a pleural effusion is not due to mesothelioma and cancer-free individuals with a history of asbestos exposure (including foundry, mechanics, plumbers, ship builders, machinists , tool and die workers, fitters, masons, electricians, those in the building trades, those involved in the assembly or repair, those with exposure to vermiculite insulation, and those with exposure from contact with family members who have worked with asbestos) . The study compared the levels of biomarkers called fibulin-3 in the blood, and the outpouring of the different groups of patients. They found that fibulin-3 in the blood does not vary according to age, sex or duration of exposure to asbestos. Fibulin-3 in the blood was significantly higher, however, in patients with pleural mesothelioma than in asbestos-exposed individuals without mesothelioma. In addition, fibulin-3 levels in the effusion fluid were significantly higher in patients with pleural mesothelioma than in patients with effusion caused by something else.
 

These results show that the levels of fibulin-3 in the blood plasma and effusion may help in the diagnosis and prognosis of pleural mesothelioma. The authors noted that further research on fibulin-3 are necessary before it can be used to diagnose patients in a clinical setting. They also called for further study of how fibulin-3 can be used to predict the prognosis of patients.
 

The authors called for further study of this important biomarker in order to clarify the role of fibulin-3 in the growth of mesothelioma, invasion and metastasis formation and to determine whether a molecule can be designed for a specific therapy. This study is an exciting promise of potentially improving the effectiveness of treatment, doctors can offer patients with mesothelioma.
 

This study is the result of collaboration of physicians from the New York University Langone Medical Center, Mount Sinai School of Medicine, Karmanos Cancer

 

Institute, University of Hawaii Cancer Center, University of California, Los Angeles, Swedish Cancer Institute, Fred Hutchinson Cancer Research Center, Princess Margaret Hospital, University Health Network and University of Toronto.
Levy Phillips & Konigsberg LLP are proud to have contributed to the support of this research through our donations.
 

 

WARNING: Mesothelioma has no known cure and often causes severe pain, suffering, and other damages, such as loss of consortium and loss of income. In addition, due to the extremely high cost of treatment of mesothelioma, many families exhaust savings and accumulation of financial debt to pay for the medical expenses of their family members.
In accordance with the law of most states, the pain and suffering from mesothelioma can be compensated by an award of monetary damages are usually obtained with the help of experienced lawyers mesothelioma. In some states, other types of damage can be repaired.
Asbestos Mesothelioma court allows victims to obtain financial compensation and to prosecute companies that caused their asbestos exposure.
 

 

IMPORTANT: If you or a family member has been diagnosed with mesothelioma, you should get in touch with a mesothelioma lawyer as soon as possible to determine if you have a mesothelioma case, as well as:
Save your right to bring a lawsuit against the responsible parties in the limited time allowed by law, known as the statute of limitations;Get maximum compensation in your case, being able to:Preserve evidence and establish the facts of asbestos exposure while the claimant is still alive and able to provide information;File and resolve a lawsuit against the responsible parties before they file for bankruptcy or if they already have to be compensated up to their bankruptcy trust funds run out of money;Speed ​​up your case, the courts tend to give a higher priority to mesothelioma claims, the applicant is still alive.Find out if you have a case, speak to one of our experienced mesothelioma lawyers through our 24/7 toll free hotline 1-800-MESO-LAW (1-800-637-6529) or by submitting an e-mail request (see education is higher). Our attorneys will quickly respond to you and happy to answer all your questions.
NOTE: While our offices are located in the states of New York, New Jersey, Georgia and California, many of our mesothelioma lawyers licensed to practice law in a number of U.S. states and have the ability and extensive experience representing clients throughout the United States mesothelioma.

You or a loved one have, or suspect you have mesothelioma? You have good reason to believe that you could develop mesothelioma or lung cancer in the future? You may have a valid claim for asbestos-caused mesothelioma, lung cancer or other diseases - and you should talk to a lawyer mesothelioma California with a proven track record with similar claims.
Reeves Law Group lawyers experienced lawyers who have helped thousands of personal injury victims to receive compensation for your injuries and damages. If you or someone you love has contracted mesothelioma, asbestosis, lung cancer, or any other asbestos-related diseases, please contact an experienced personal injury lawyer in Reeves Law Group in California. You can contact our law firm at (800) 644-8000 for a free consultation with a lawyer.

What are the special problems for you and your lawyer will have to face as a result of your asbestos-related mesothelioma or claims lung cancer?
On the one hand, there is a real risk that, if you or a loved one has been diagnosed with mesothelioma or lung cancer, time is of the essence, the life expectancy of malignant mesothelioma and lung cancer victims is limited. Your claim asbestos lawyer should take the time to discuss with the victim the possible sources of his or her exposure to asbestos and training effects of mesothelioma, lung cancer or asbestosis has had on the life of the sufferer. The lawyer may need to deposition of the victim (out of court testimony), where possible, in the event that the person will not be able to testify in court.
Another complication of asbestos claims over time from exposure to diagnosis. Your California mesothelioma attorney and his team of researchers to investigate the events that occurred long ago, and the location of the parties to accept the testimony of witnesses who can now retired or moved. Your lawyer may need to look for secondary data asbestos contamination - perhaps to find out if other people, you have worked with contract mesothelioma or lung cancer, because the physical evidence that was asbestos contamination in the workplace 30 years ago, is now gone.
Finding all possible sources of liability will be particularly important to you and your attorney to handle the case of mesothelioma or lung cancer, as many producers of asbestos products have declared bankruptcy, or may do so in the future. Competent and experienced lawyer asbestos claim will work to exhaustively investigate your case history to find all the possible responsible parties. If you worked in the shipbuilding industry, for example, your attorney should know about all your employers for many years. Then, if the asbestos dust manufacturer filed for bankruptcy, your attorney may be able to help you receive compensation from other responsible parties.

Friday, 12 October 2012 20:16

Asbestos causes lung cancer.

 

  Lung cancer can also be caused by frequent contact with asbestos, so that all who are exposed to asbestos should watch for signs of this cancer. When the strike of lung cancer cells grow uncontrollably in the lungs, eventually forming a malignant tumor in the airway, making it difficult to breath.
Lung cancer kills more Americans each year than any other type of cancer. In 2007, the number of U.S. deaths from lung cancer was more than 160,000. Lung cancer is also the most common diseases related to asbestos exposure, and because lung cancer is often caused by other agents - like cigarette smoke - the less people know that exposure to asbestos can cause or aggravate lung cancer.
According to the American Lung Association, and the people who work around asbestos who do not smoke are five times more likely to develop lung cancer than people who do not smoke and does not undergo a significant amount of asbestos. If a person is exposed to a large number of asbestos and smoking, their chance of contracting lung cancer increased significantly. In fact, the Centers for Disease Control and Prevention reports that various studies have shown smokers who are exposed to asbestos from 50 to 84 times more likely to develop lung cancer than smokers who do not come in contact with a large number of asbestos.
Type of treatments offered for lung cancer depends on the extent of disease, age and health of the patient and the tumor (s). These treatments may include chemotherapy, radiation therapy, surgical removal of all or part of the cancerous tissue and maintenance treatment to reduce discomfort.

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